Sodatide Clostridium Butyricum: What Does the Label Say About This Bacterium?

The Supplement Facts panel lists a probiotic blend of 36 mg per capsule. Three species share that weight: Bifidobacterium infantis, Clostridium butyricum and Akkermansia muciniphila. This post looks at the middle one, Sodatide Clostridium butyricum, because it raises the most safety questions.

The panel does not say how much of the 36 mg each species gets. It also gives no CFU count, which is the number of live cells, and no strain code. The label tells you the species name and nothing more about it.

• Clostridium butyricum is one of three bacteria in the 36 mg probiotic blend.
• The other two are Bifidobacterium infantis and Akkermansia muciniphila.
• CFU per strain and strain codes are not published.
• A 2024 report described five rare bloodstream infections from C. butyricum probiotics, mostly in people with weak immune systems.
• Pregnant or nursing women, children under 18 and people with a known medical condition should ask a physician first.
• Sodatide is not FDA approved and is not a medicine.
• Each bottle holds 30 capsules at one capsule a day.

The name points to what it makes: butyrate, a short-chain fatty acid. It also forms spores, a tough resting stage that helps it survive stomach acid and storage. It has been sold as a probiotic in Japan for many years.

Butyrate is one of the short-chain fatty acids that gut bacteria make when they ferment fiber. Each Sodatide capsule also holds 211 mg of chicory root inulin and 100 mg of potato resistant starch, which are the fibers bacteria feed on. The idea behind the formula is fiber plus bacteria in one capsule. No trial of the finished capsule has been published, so that is an idea and not a result. Keep that in mind when you read about Sodatide Clostridium butyricum anywhere else.

Probiotic research is tied to exact strains. Letters and numbers after the species name identify the strain, and a result for one strain does not carry over to another.

Safety work on one strain, named MIYAIRI 588, found it lacked the main toxin genes linked to harmful Clostridium species. The label does not say which strain Sodatide uses, so that result cannot be applied to it directly. This is a gap in what is published, not a finding about the capsule.

A 2024 report from Japan described five rare bloodstream infections traced to Clostridium butyricum probiotics. Most of the people affected had weakened immune systems. For healthy adults this is not a common concern, but it is the reason to be careful.

Talk to your doctor first if any of these apply to you:

• You have a weakened immune system or take drugs that lower immunity.
• You have a serious illness or a known medical condition.
• You are pregnant or nursing.
• You are under 18.
• You take any medicine and are unsure about it.

Fever or chills while taking a probiotic are very rare. If they happen, stop and see a doctor the same day, and tell them the product contains C. butyricum. Our side effects page sets out the full picture.

Bifidobacterium infantis belongs to the group of bacteria that inulin feeds. Akkermansia muciniphila is the species behind a trial that used 10 billion pasteurized cells a day. Clostridium butyricum is the butyrate maker of the three.

None of that tells you how the three behave together in a 36 mg blend. The label does not publish counts for any of them. If you want to understand the star species better, read our post on Akkermansia muciniphila and the ingredients page.

Sodatide Clostridium butyricum is a named species with a clear job in the idea behind the formula, but the facts that would let you judge it are not printed. There is no CFU count and no strain code, so you cannot match it to a study.

For most healthy adults the bigger daily question is simple use: one capsule with water and the bottle in the fridge after opening. If any of the caution groups above is you, speak to your doctor first. Sodatide is a supplement, not FDA approved, and not meant to treat any disease.

Last updated October 26, 2026.